“Our study has identified genes that play a crucial role in the neuronal control of body weight. They act in the brain in pathways that may affect people s food intake, hunger and satiety,” said Ruth Loos, lead author of the study and professor at The Charles Bronfman Institute for Personalized Medicine at the .Genes can directly cause obesity in disorders such as Bardet Biedl syndrome and Prader Willi syndrome. Identification of those genes will help clarify the etiology of obesity and its metabolic consequences, the metabolic complications of obesity, as well as identify at risk individuals or groups in terms of their genetic .Obesity results from the energy imbalance that occurs when a person consumes more calories than their body burns. Obesity is a serious public health problem because it is associated with some of the leading causes of in the U.S. and worldwide, including diabetes, heart disease, stroke, and some types of cancer..Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. Stu.s have identified variants in several genes that may contribute to weight gain and body fat distribution although, only in a few cases are genes the primary cause of obesity. Polymorphisms in various .
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