. Salk scientists modify CRISPR to epigenetically treat diabetes, kidney disease, muscular dystrophy. Approach could also be applied to reversing aging and age related diseases such as hearing loss and macular degeneration. Home Salk News Salk scientists modify CRISPR to epigenetically treat .Salk scientists have created a new version of the CRISPR Cas genome editing technology that allows them .The system relies on recruitment of Cas and transcriptional activation complexes to target loci by modified single guide RNAs. As proof of concept, we used this technology to treat mouse models of diabetes, muscular dystrophy, and acute kidney disease. Results demonstrate that CRISPR Cas mediated .As a proof of concept, the Salk group used their new approach to treat several diseases, including diabetes, acute kidney disease, and muscular dystrophy, in mouse models. Juan Carlos Izpisua Belmonte, a professor in Salk s Gene Expression Laboratory and senior author of the new paper said, "Although .
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